Kubhubhani we-COVID-19, ukubonelela ngokhathalelo lwempilo olwaneleyo kwizigulana kubalulekile ukugcina ukusweleka kusezantsi.Izinto zonyango, ngakumbi abasebenzi benkonzo yonyango olungxamisekileyo, abamele umgca wokuqala womlo ochasene ne-COVID-19 [1].Kukwiseti yangaphambi kwesibhedlele apho isigulana ngasinye kufuneka siphathwe njengesigulana esinokosulela, kwaye iveze ngokukodwa izinto zonyango ezisebenza kumgca ongaphambili kumngcipheko wosulelo lwe-SARS-CoV-2 [2].Kuphononongo olucwangcisiweyo, i-Bandyopadhyay et al.ukuhlola idatha ye-152,888 HCWs usulelo lubonisa ukufa kwi-0.9% kwinqanaba [3].Nangona kunjalo, babala ukufa-
kwinqanaba lama-37.2 lokusweleka kwi-100 losulelo lwe-HCWs kwiminyaka engama-70.URivett et al.Uphononongo lwe-3% yovavanyo kwiqela le-HCW lokuhlola i-asymptomatic yayiyi-SARS-CoV-2 positive [4].Uvavanyo oluchanekileyo luvumela ukuchongwa kwabantu abanokufuna unyango, okanye ekufuneka bazimele bodwa ukuthintela ukusasazeka kosulelo.Ngokumalunga noku ngasentla, ukuhlolwa kwezinto zonyango oluphuthumayo kunye neempawu ezincinci okanye ezingenazo iimpawu eziya kuba zibalulekile ekukhuseleni izigulane
kunye nabo bonke abasebenzi bezonyango.
Umzobo 1. Uzifunda njani iziphumo zovavanyo.
Ukufumaneka okwandayo kweemvavanyo ze-antigen kuvumela ukusetyenziswa kwazo esibhedlele, ngaphambi kwesibhedlele kunye nezicwangciso zekhaya.Ubume bovavanyo lwe-immunoloji yokufumanisa ii-antigens ze-AG zibonakalisa usulelo lwangoku lwe-SARS-CoV-2 intsholongwane [5].Okwangoku, iimvavanyo ze-antigen ziye zaqatshelwa njengezilingana neemvavanyo zofuzo ezenziwa yi-RT-qPCR.Ezinye iimvavanyo zifuna umzekelo wempumlo onokuqokelelwa kusetyenziswa i-swab yempumlo yangaphambili okanye i-nasal mid-turbinate swab, enye ifuna isampuli yamathe.Inyathelo elilandelayo emva kokuqokelela imathiriyeli yebhayoloji kukuyixuba nolwelo lwesidambisi.Ke, emva kokufaka amathontsi ambalwa (kuxhomekeke kumenzi wovavanyo) wesampulu efunyenweyo kuvavanyo, i-golden-antibody conjugate is hy-drated kunye ne-COVID-19 antigen, ukuba ikhona kwisampulu, iya kusebenzisana izilwa-buhlungu zegolide.I-antigen-antibody-gold com-plex iya kufudukela kwifestile yovavanyo ukuya kuMmandla woVavanyo, apho iya kubanjwa khona ngama-antibodies angenakunyakaziswa, okwenza umgca wepinki obonakalayo (i-Assay Band) ebonisa umphumo omuhle.Inzuzo yovavanyo lwe-antigen olukhawulezayo, olusekwe kwi-lateral flow immunochromatographic as-says (LFIA), lixesha elifutshane lokufunyaniswa, ngelixa izinto ezingalunganga zinobuntununtunu obuphantsi kune-RT-qPCR kunye nethuba lokufumana isiphumo esibi kumntu osulelekileyo. kunye ne-SARS-CoV-2.Uphononongo olupapashwe ekuqaleni kobhubhani we-COVID-19 lubonise ukuba ubuntununtunu besizukulwana sokuqala sovavanyo olukhawulezayo lokufumanisa ii-antigens ze-SARS-CoV-2 kwisampulu evavanyiweyo zisusela kwi-34% ukuya kuma-80% [6].Enkosi ekufumaneni iziphumo kwimizuzu nje embalwa okanye embalwa, isizukulwana sesibini sovavanyo lwe-antigen sisixhobo esikhawulezayo nesifanelekileyo sokuxilonga, kwaye kule mihla ukusebenza kwayo kuphezulu njengobuntununtunu ≥90% kunye nokucaciswa ≥97% .Umzekelo wovavanyo olunjalo luvavanyo olukhawulezayo lwe-antigen ye-COVID-19 (SG Diagnostics, Singapore), imiyalelo yokutolikwa kweziphumo yanikezelwa kumfanekiso woku-1.
Iimvavanyo ze-antigen nazo zafumana ukuqatshelwa kokuvavanya izigulane esele zilungele kwisigaba sangaphambi kwesibhedlele.Umzekelo wokusetyenziswa kovavanyo lwe-antigen ye-COVID-19 kwinqanaba lokhathalelo lwe-prehospital inokuba ziiNkonzo zezoNyango eziNgxamisekileyo eWarsaw (ePoland), apho sonke isigulana esirhanelwa ukuba sine-COVID-19 okanye sinxibelelana nesigulana sixhomekeke kwi-diag-nosis ekhawulezayo. uvavanyo, enkosi apho aboncedo lokuqala bayazi ukuba kufuneka basiwe kwisibhedlele esinikezelwe kwizigulana ze-COVID-19 okanye isibhedlele esiqhelekileyo [7].Uvavanyo olukhawulezayo lwe-antigen kufuneka lusetyenziswe ukucofa usulelo lwe-SARS-CoV-2 lwempumlo ikakhulu kwizigulana ezineempawu ngexesha leentsuku zokuqala ezi-5-7 emva kokuqala kweempawu.Abantu abaneempawu ezineziphumo zovavanyo lwe-antigen ye-SARS-CoV-2 kufuneka baphathwe njengosulelekile.Iziphumo ezibi zolu vavanyo zifuna ukuqinisekiswa ukuba umfanekiso weklinikhi okanye indawo ebalulekileyo ye-epidemiological ibonisa usulelo lwe-COVID-19, kuba iziphumo ezibi zovavanyo lwe-antigen alulubandakanyi usulelo lwentsholongwane.
Isishwankathelo, ukuhlolwa kwezinto zonyango olungxamisekileyo kunye nezigulane ze-EMS ezinobuncinci okanye ezingenazo iimpawu yindlela eya kuba yinto ebalulekileyo ekukhuseleni izigulane kunye nabo bonke abasebenzi bezonyango.
Ixesha lokuposa: Nov-27-2021